Written by Divinity Nutra, Updated on March 13, 2023

Skin Inflammation

Skin inflammation can be caused by a variety of factors, including irritants, allergens, and underlying medical conditions. The resulting symptoms of inflamed skin can range from mild redness and itching to more severe rashes and blisters.

Proper diagnosis and treatment are important for managing skin inflammation and preventing further complications. In this article, we will explore the various causes of skin inflammation, how it is diagnosed, and available treatment options.

What Is Skin Inflammation?

Skin inflammation, also known as dermatitis, is a common condition characterized by redness, swelling, itching, and/or pain of the skin. It is typically caused by an immune system response to an irritant, allergen, or another trigger, and can affect people of all ages and skin types. Inflammation of the skin can be acute or chronic and may be accompanied by other symptoms such as blisters, scaly patches, or oozing sores.

Causes of Skin Inflammation

What causes skin inflammation? Many things can lead to inflamed skin. Here are the most common causes of inflammation you need to be aware of.


Allergic reactions occur when the immune system overreacts to a substance in the environment, such as pollen, pet dander, or certain foods. When allergens come into contact with the skin, they can trigger an immune response and cause skin inflammation. This can manifest as redness, swelling, itching, and other symptoms.


Infections cause skin inflammation through the activation of the immune system in response to pathogens that invade the skin. This causes redness, swelling, and warmth in the affected area. In addition, the body produces immune cells that fight off the infection, leading to the formation of pus and the destruction of skin tissue.

Autoimmune Conditions

Autoimmune conditions cause skin inflammation as a result of the body’s immune system attacking healthy skin cells, causing the skin to become red, itchy, and inflamed. Common autoimmune conditions that can cause skin inflammation include lupus, psoriasis, and scleroderma. The severity and duration of skin inflammation will depend on the specific autoimmune condition and its progression.


Photosensitivity can cause skin inflammation by triggering a reaction to UV radiation. In photosensitive individuals, exposure to sunlight can cause redness, rash, itching, and blistering on the skin. This can occur as a result of certain medications, autoimmune conditions, or genetic predisposition.

Heat Rash

Heat rash, also known as prickly heat, occurs when sweat ducts become blocked and sweat accumulates under the skin. The trapped sweat can cause skin irritation, redness, and inflammation, leading to a rash that is typically itchy and uncomfortable. The rash is often seen in areas of the body where clothing or equipment rubs against the skin, such as the neck, back, chest, or groin.

Sun Damage

Sun damage to the skin can cause inflammation due to the ultraviolet (UV) radiation from the sun. UV radiation can lead to the formation of reactive oxygen species (ROS) which cause oxidative stress and cellular damage. This cellular damage triggers an inflammatory response as the body tries to repair the damage, resulting in redness, swelling, and pain. Over time, chronic sun exposure can lead to chronic inflammation, which can increase the risk of skin cancer and other skin disorders.

Other Factors

Several other factors can lead to skin inflammation, including irritants, such as harsh soaps, detergents, and chemicals; friction, as may occur with tight clothing or repetitive rubbing; dry skin; stress; hormonal changes; and even certain medications. In some cases, underlying medical conditions, such as rosacea or eczema, may also contribute to skin inflammation. Additionally, environmental factors such as air pollution and smoking can exacerbate skin inflammation.

Symptoms of Skin Inflammation

What does skin inflammation look like? The classic signs of inflammation of the skin are:

  • Redness: The affected skin may appear reddened or flushed.
  • Swelling: The skin may appear swollen or puffy.
  • Itching: The affected skin may feel itchy or irritated.
  • Pain: The inflamed area may be painful or tender to the touch.
  • Warmth: The skin in the affected area may feel warm to the touch.
  • Rash: A rash may be present on the skin.
  • Blisters: Blisters may form on the affected area.
  • Dryness: The skin may feel dry or scaly or appear cracked.
  • Crusting: The affected area may develop a crust or scab.
  • Ulcers: In severe cases, open sores or ulcers may develop.

How to Diagnose Skin Inflammation

Diagnosing skin inflammation typically involves a physical examination by a healthcare provider, who will look for visible signs of inflammation on the skin. The provider may also ask about the patient’s medical history, including any previous skin conditions or exposure to allergens or irritants.

In some cases, a skin biopsy or blood test may be done to confirm a diagnosis or rule out other conditions. The skin biopsy involves taking a small sample of skin tissue to examine under a microscope, while a blood test can help identify underlying conditions such as autoimmune disorders or infections that may be contributing to the inflammation.

Ultimately, the specific tests used to diagnose skin inflammation will depend on the suspected cause of the inflammation and the patient’s individual medical history and symptoms.

Inflammatory Skin Conditions

What are the most common inflammatory skin conditions? There are several common inflammatory skin conditions. Some of the most common include:

  • Eczema: A group of conditions that cause the skin to become inflamed, itchy, and red.
  • Psoriasis: A chronic autoimmune condition that causes red, scaly patches to develop on the skin.
  • Rosacea: A common skin condition that causes redness and visible blood vessels in the face, as well as acne-like bumps.
  • Contact dermatitis: An itchy, red rash caused by contact with an allergen or irritant.
  • Hives: An itchy rash that develops when the immune system releases histamine in response to an allergen or irritant.
  • Acne: A common skin condition that occurs when hair follicles become clogged with oil and dead skin cells, leading to inflammation and pimples.
  • Lichen planus: An inflammatory skin condition that causes itchy, flat-topped bumps to develop on the skin and mucous membranes.
  • Pityriasis rosea: A common skin condition that causes a rash to develop on the torso, arms, and legs.

There are many other types of inflammatory skin conditions as well, and they can vary in severity and symptoms.

Treatment of Skin Inflammation

How do you reduce skin inflammation and redness? The treatment of inflammatory skin conditions depends on the specific condition and the severity of the symptoms. However, some general treatment options for skin inflammation are listed below.

Topical Medications

Topical medications are creams, ointments, or lotions that can be applied directly to the skin to treat inflammation. The most common types of topical medications used for treating skin inflammation are:

  • Corticosteroids: These medications are anti-inflammatory and can be applied topically to reduce swelling, redness, and itching. They work by suppressing the immune response that causes inflammation.
  • Topical calcineurin inhibitors: These are immunosuppressive drugs that are used to treat eczema and other inflammatory skin conditions. They work by inhibiting the activity of certain immune cells and reducing inflammation.
  • Topical retinoids: These treatments are derived from vitamin A and are used to treat acne and other inflammatory skin conditions. They work by unclogging pores and reducing inflammation.
  • Topical antibiotics: These medications are used to treat bacterial infections that can cause inflammation. They work by killing bacteria and reducing inflammation.
  • Topical antifungals: These drugs are used to treat fungal infections that can cause inflammation. They work by killing the fungi and reducing inflammation.
  • Topical antihistamines: These medications are used to treat allergic skin reactions that cause inflammation. They work by blocking the release of histamine, which is responsible for the allergic reaction.
  • Moisturizers: These are non-medicated topical treatments that can help soothe and hydrate inflamed skin. They work by helping to repair the skin barrier and reducing dryness and irritation.

Different types of topical medications have different side effects and interactions, so it’s important to use them as directed under the guidance of a healthcare professional.

Oral Medications

Oral medications can be used to treat skin inflammation, such as:

  • Corticosteroids: These drugs reduce inflammation by suppressing the immune system. They can be administered orally and are usually prescribed for short periods to avoid side effects.
  • Antihistamines: These medications block histamine, which is a chemical that is released during an allergic reaction. Antihistamines can be used to treat itching, swelling, and redness of the skin.
  • Antibiotics: Antibiotics can be prescribed to treat bacterial skin infections, which can cause inflammation. These drugs can be taken orally or applied topically, depending on the severity of the infection.
  • Immunosuppressants: These drugs suppress the immune system and can be used to treat severe skin inflammation that is not responsive to other treatments.
  • Retinoids: These drugs are used to treat skin conditions such as acne, psoriasis, and eczema. Retinoids work by reducing inflammation and regulating skin cell growth. They are available in oral and topical forms.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs can be used to reduce inflammation and pain. These anti-inflammatory drugs are often used to treat skin conditions such as hives, eczema, and psoriasis. Common NSAIDs include aspirin, ibuprofen, and naproxen.

It’s important to note that these medications should only be taken as prescribed by a healthcare provider, as they can cause side effects and interact with other medications.

Home Remedies

Here is a list of home remedies for inflammation that can also help treat skin inflammation:

  • Cool compress: Applying a cool compress to the affected area can help soothe inflammation and reduce swelling.
  • Oatmeal baths: Taking an oatmeal bath can help relieve itchy and inflamed skin.
  • Aloe vera: Applying aloe vera gel to the affected area can help reduce inflammation and redness.
  • Tea tree oil: Applying diluted tea tree oil to the affected area can help reduce inflammation and kill bacteria.
  • Chamomile tea: Applying a chamomile tea bag to the affected area can also help reduce inflammation and redness.
  • Honey: Applying raw honey to the affected area can help lower inflammation and moisturize the skin.

When to Call Your Doctor

You should call your doctor if you have severe skin inflammation and it doesn’t improve with self-care measures, is spreading or affecting a large area of your body, is accompanied by other symptoms such as fever or pain, or if it is interfering with your daily life.

It’s important to seek medical attention if you are concerned about your symptoms or if they are not improving, as your doctor can help determine the underlying cause and provide appropriate treatment.

Severe symptoms of skin inflammation that might be a concern and require immediate medical attention include:

  • Fever
  • Extreme pain or discomfort
  • Severe itchiness
  • Pus, drainage, or oozing from the skin
  • Swelling, warmth, or redness spreading to other parts of the body
  • Difficulty breathing or swallowing
  • Rapid heart rate or breathing
  • Swelling of the face, tongue, or throat
  • Blistering or peeling of the skin
  • Fainting or loss of consciousness

If you experience any of these symptoms, seek medical attention immediately.

How to Prevent Skin Inflammation

There are several ways to prevent skin inflammation:

  • Avoid irritants: To prevent skin inflammation, it is important to avoid irritants that can trigger an inflammatory response. Common irritants include harsh soaps, detergents, and fragrances.
  • Protect your skin from the sun: Exposure to the sun’s ultraviolet rays can cause skin inflammation. To protect your skin, wear sunscreen with an SPF of 30 or higher and limit your time in the sun.
  • Keep your skin moisturized: Dry skin can be more susceptible to inflammation. Using a moisturizer can help keep your skin hydrated and prevent inflammation.

How to Reduce Inflammation Naturally

Can skin inflammation go away? There are several natural ways to reduce inflammation in the body, including:

  • Eliminate inflammatory foods: Avoid foods that cause inflammation like processed and fried foods, refined sugars, and artificial ingredients.
  • Eat foods that reduce inflammation: Eat more anti-inflammatory foods such as fatty fish, nuts, seeds, fruits, and vegetables.
  • Make lifestyle modifications: Regular exercise, getting enough sleep, and reducing stress can all help reduce inflammation in the body.
  • Take dietary supplements: Natural herbs and spices such as ginger, curcumin (found in turmeric), and garlic can help reduce inflammation in the body.

Here are the three best anti-inflammatory supplements that you can take daily to reduce inflammation.

Turmeric contains an active ingredient called curcumin, which has potent anti-inflammatory properties. Curcumin works by blocking pro-inflammatory cytokines and neutralizing harmful free radicals that cause inflammation.

Apple cider vinegar helps reduce inflammation by increasing the acidity of the body, which in turn helps to maintain the natural pH balance. This can help to reduce inflammation and support overall health.

Elderberry is rich in anthocyanins, which are known for their antioxidant and anti-inflammatory properties. These compounds inhibit the production of pro-inflammatory compounds in the body.

Inflammation of the Skin: Final Thoughts

Skin inflammation can be caused by a variety of factors and can manifest in many different ways. It is important to identify the underlying cause of skin inflammation to effectively treat it.

By practicing good skin care habits, seeking medical attention when necessary, and making lifestyle changes, individuals can help reduce and prevent inflammation of the skin. With proper diagnosis and treatment, those with skin inflammation can find relief and achieve healthier happier skin.